Grey Cases in Cardiology and Maneuvering in a Grey Zone, Where a Grey Attitude May Yield a Black Outcome

Grey zone in medicine and namely, in cardiology, represents a perplex area that clinicians have to navigate through and deal with. Grey cases in medicine represent intricate situations and the great challenge is to maneuver appropriately in order to narrow the grey zone and/or to move grey cases out of it. This may be achieved every so often by a comprehensive clinical approach, along with an extension of paraclinical tests. However, there are situations where grey cases remain in the grey zone, despite all efforts, and this may be related to the current medical progress. In cardiology, dealing with grey cases is critical given the risk of sudden cardiac event. Herein, we present two cases that illustrate grey zone in cardiology: a case of Brugada pattern in a 9-year-old-female patient and a case of acute heart failure with indeterminate brain natriuretic peptide levels. Discussion is made in the light of the relevant data from the